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MLS-M 430: ADVANCED GENE REGULATION: TRANSCRIPTION, EPIGENETICS AND HUMAN DISEASE (3 credits)

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Considers mechanistic, structural and regulatory aspects of the process by which information coded in DNA is transcribed into messenger and structural RNAs. Investigates the role of post-translational modification on nucleosome tails and on the RNA polymerase itself to regulate the timing and extent of transcription. Examines how regulatory marks are written and interpreted.

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